Dominic N Reeds Selected Research

xenin 25 (xenin)

1/2018	Cholinergic signaling mediates the effects of xenin-25 on secretion of pancreatic polypeptide but not insulin or glucagon in humans with impaired glucose tolerance.
2/2014	Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes.
11/2013	The combination of GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitus.
7/2012	Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.

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Dominic N Reeds Research Topics

Disease

19	Insulin Resistance 02/2022 - 05/2005
9	Glucose Intolerance 01/2023 - 10/2006
8	Type 2 Diabetes Mellitus (MODY) 01/2023 - 10/2006
8	Hyperinsulinism (Hyperinsulinemia) 01/2022 - 10/2006
8	Weight Loss (Weight Reduction) 05/2018 - 05/2009
7	Overweight 01/2020 - 05/2011
6	Obesity 02/2022 - 10/2016
6	Barth Syndrome 11/2021 - 02/2017
3	Prediabetic State (Prediabetes) 01/2023 - 01/2020
3	Inflammation (Inflammations) 07/2015 - 06/2012
2	Hyperglycemia 01/2023 - 10/2006
2	Cardiomyopathies (Cardiomyopathy) 01/2021 - 12/2020
2	Muscular Diseases (Myopathy) 02/2017 - 01/2013
2	Birth Weight (Birth Weights) 01/2016 - 08/2015
2	Infections 01/2016 - 03/2009
2	HIV Infections (HIV Infection) 07/2015 - 12/2011
2	Sarcopenia 07/2015 - 02/2011
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2023
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023
1	Obstructive Sleep Apnea 02/2022
1	Ulcer 01/2016
1	Diarrhea 01/2016
1	Wounds and Injuries (Trauma) 01/2016
1	Sepsis (Septicemia) 01/2016
1	Cardiovascular Abnormalities 08/2015
1	Myocardial Infarction 07/2015
1	Stroke (Strokes) 07/2015
1	Vascular Diseases (Vascular Disease) 07/2015
1	Necrosis 03/2013
1	Morbid Obesity 11/2012
1	Body Weight (Weight, Body) 08/2012
1	Atherosclerotic Plaque (Atheroma) 06/2012
1	Viremia 06/2012
1	Rupture 06/2012
1	Atherosclerosis 06/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2012
1	Arteritis 06/2012
1	Chronic Renal Insufficiency 02/2012
1	Left Ventricular Dysfunction 12/2011

Drug/Important Bio-Agent (IBA)

34	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 10/2006
20	Insulin (Novolin)FDA Link 02/2022 - 10/2006
8	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 03/2007
8	Proteins (Proteins, Gene)FDA Link 11/2021 - 03/2009
5	Amino Acids FDA Link 12/2020 - 10/2006
4	Triglycerides (Triacylglycerol)IBA 02/2022 - 05/2009
4	Nonesterified Fatty Acids (NEFA)IBA 01/2022 - 08/2012
4	LipidsIBA 01/2022 - 08/2013
4	Leucine (L-Leucine)FDA Link 05/2018 - 10/2006
4	xenin 25 (xenin)IBA 01/2018 - 07/2012
3	PalmitatesIBA 02/2022 - 01/2017
3	Cholinergic Agents (Cholinergics)IBA 01/2018 - 11/2013
3	Peptides (Polypeptides)IBA 01/2017 - 11/2013
3	IsotopesIBA 01/2016 - 08/2012
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 07/2015 - 02/2011
3	VLDL LipoproteinsIBA 08/2013 - 02/2012
3	Muscle Proteins (Muscle Protein)IBA 09/2011 - 10/2009
2	Pancreatic Polypeptide (Pancreatic Polypeptide (PP))IBA 01/2018 - 11/2013
2	AdiponectinIBA 01/2017 - 01/2011
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2016 - 07/2015
2	Pioglitazone (Actos)FDA Link 11/2013 - 01/2011
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2013 - 01/2011
2	Apolipoprotein B-100 (Apo B 100)IBA 08/2013 - 08/2012
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 02/2011 - 10/2009
2	Protease Inhibitors (Protease Inhibitor)IBA 03/2007 - 05/2005
1	Phosphates (Orthophosphate)IBA 01/2021
1	Arginine (L-Arginine)FDA Link 12/2020
1	ChylomicronsIBA 01/2020
1	Therapeutic UsesIBA 05/2018
1	Whey ProteinsIBA 05/2018
1	Glucagon (Glukagon)FDA Link 01/2018
1	Oxygen (Dioxygen)IBA 01/2018
1	Cardiolipins (Cardiolipin)IBA 02/2017
1	CytokinesIBA 01/2017
1	LeptinIBA 01/2017
1	C-Reactive ProteinIBA 09/2016
1	Bethanechol (Duvoid)FDA LinkGeneric 01/2016
1	AnticoagulantsIBA 01/2016
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016
1	C-PeptideIBA 07/2015
1	IncretinsIBA 07/2015
1	Sitagliptin Phosphate (Januvia)FDA Link 07/2015
1	Fish OilsIBA 07/2015
1	Hormones (Hormone)IBA 07/2015
1	Branched-Chain Amino AcidsIBA 05/2015
1	Acetaminophen (Paracetamol)FDA LinkGeneric 02/2014
1	PPAR gammaIBA 11/2013
1	very low density lipoprotein triglycerideIBA 08/2013
1	LDL CholesterolIBA 08/2012
1	GlucocorticoidsIBA 08/2012
1	HDL CholesterolIBA 08/2012
1	Lipoproteins (Lipoprotein)IBA 08/2012
1	Dexamethasone (Maxidex)FDA LinkGeneric 08/2012
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/2012
1	Biomarkers (Surrogate Marker)IBA 06/2012

Therapy/Procedure

6	Therapeutics 10/2016 - 05/2011
4	Highly Active Antiretroviral Therapy (HAART) 07/2015 - 05/2005
2	Caloric Restriction 05/2009 - 03/2009
1	Catheters 01/2016
1	Home Parenteral Nutrition 01/2016
1	Injections 03/2013